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Cover of Analyzing Data Handbbook Chapter

The “Analyzing Data (Trials): Handbook Chapter” resource is an excerpt of the PROTEUS-Trials Handbook summarizing the preliminary SISAQOL recommendations for PRO data analysis; work is continuing via the SISAQOL-IMI initiative.

View the entire Handbook here (US version) or here (UK version).

Citation Information
When referencing information included in the PROTEUS-Trials Handbook, we recommend citing the primary sources rather than the Handbook.

To reference the Handbook itself, please use:

The PROTEUS-Trials Consortium (Patient-Reported Outcomes Tools: Engaging Users & Stakeholders). PROTEUS Handbook. Prepared by The University of Sydney Quality of Life Office for the PROTEUS-Trials Consortium. Available at

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